Clinical Response of Convalescent Plasma Therapy in COVID-19 Patients in Dr. Saiful Anwar General Hospital
DOI:
https://doi.org/10.21776/ub.jkb.2021.031.04.5Keywords:
COVID-19-Convalescent Plasma-reduce mortalityAbstract
The use of convalescent plasma has been beneficial for more than a century to treat various infections. The lack of effective treatment currently available for COVID-19 has reemerged the use of convalescent plasma as a potential therapeutic option. This is an observational descriptive study in 13 COVID-19 patient who got convalescent Plasma. Consist of 11 (84%) male patient, 2 (16%) female patient. Divided into two groups based on severity, and outcome. 38% patient included in severe disesase and 62% patient in critically Ill condition. 30% patient who got convalescent plasma deceased, and 70% had a resolve condition.
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Cascella M, Rajnik M, Aleem A, Dulebohn SC, and Napoli RD. Features, Evaluation, and Treatment of Coronavirus (COVID-19). (Online) 2021 Jul 30. https://www.ncbi.nlm.nih.gov/books/NBK554776/
Wang C, Wang Z, Wang G, Lau JYN, Zhang K, and Li W. COVID-19in Early 2021: Current Status And Looking Forward. Signal Transduction and Targeted Therapy. 2021; 6(1): 1-14.
Muhyiddin and Nugroho H. A Year of Covid-19: A Long Road to Recovery and Acceleration of Indonesia's Development. The Indonesian Journal of Development Planning. 2021; 5(2): 1-19.
Li L, Zhang W, Hu Y, et al. Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19: A Randomized Clinical Trial. Journal of American Medical Association. 2020; 324(5): 460-470.
Rajendran K, Krishnasamy N, Rangarajan J, Rathinam J, Natarajan M, and Ramachandran A. Convalescent Plasma Transfusion for the Treatment of COVID-19: Systematic Review. Journal of Medical Virology. 2020; 92(9): 1475-1483.
Duan K, Liu B, Li C, et al. Effectiveness of Convalescent Plasma Therapy in Severe COVID-19 Patients. Proceedings of the National Academy of Sciences of the United States of America. 2020; 117(17): 9490-9496.
Shen C, Wang Z, Zhao F, et al. Treatment of 5 Critically Ill Patients with COVID-19 with Convalescent Plasma. Journal of American Medical Association. 2020; 323(16): 1582-1589.
Casadevall A, Joyner MJ, and Pirofski LA. A Randomized Trial of Convalescent Plasma for COVID-19-Potentially Hopeful Signals. Journal of American Medical Association. 2020; 324(5): 455-457.
Rojas M, RodrÃguez Y, Monsalve DM, et al. Convalescent Plasma in Covid-19: Possible Mechanisms of Action. Autoimmunity Reviews. 2020; 19(7): 1-9.
Yuki K, Fujiogi M, and Koutsogiannaki S. COVID-19 pathophysiology: A review. Clinical Immunology. 2020; 215: 1-8.
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