DISTRIBUSI MAST CELL PADA MESENTERIUM TIKUS

Authors

  • Mohamad N Ibrahim Jurusan Perikanan FPIK Universitas Haluoleo Kendari
  • Edi Widjajanto Laboratorium Patologi Klinik Fakultas Kedokteran Universitas Brawijaya Malang
  • Rita Rosita Laboratorium Anatomi Fakultas Kedokteran Universitas Brawijaya Malang

DOI:

https://doi.org/10.21776/ub.jkb.2008.024.02.2

Abstract

Mast cell are derived from haematopoietic progenitors in the bonemarrow. Developing mast cell subsequently
migrate to peripheral tissues, such as the skin, mucosa and air way, where they terminate their differentiation
under  the  influence  of  factors  in  the  tissue  micro-enviroment.  This  study  aimed  to  know  distribution  and
strucutre of mast cell on rat mesentery. The mesentery was stained with a 1 % safranine solution or toluidine
blue  on  the  a  pepared  slide.  The  prepared  slides  were  immediately  viewed  by  a  observer  through  a
microscope.  The  result  showed  that  mast  cells  stained  with  safranine  or  toluidine  blue  were  closely
associated with postcapillary in the rat mesentery.
Keywords : mast cell, mesentery

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References

DAFTAR KEPUSTAKAAN

Abbas, A. K.,Lichtman,A. H.,Pober, J. S. Cellular and moleculer Immunology. 2th, Elsivier Science edition Philadelphia,1994.

Krishnaswamy, G., J. Kelley The Human mast cell: Functions in physiology and disease. Bioscience, 2001;6:d1109-1127.

Widjajanto. Mast cell. Fakta dan potensinya dalam perspektif Laboratory Medicine. Pidato pengukuhan jabatan guru besar dalam bidang ilmu patologi klinik pada Fakultas Kedokteran Universitas Brawijaya Malang,2007

Kim, S. M., You, H. J., You, M. K., Kim, N. S., Sim, B. S & Kim, H. M. Inhibitory effect of water-soluble chitosan on TNF-α and IL-8 secretion from HMC-1 cells. J. Immunofpharmacology and Immunotoxicology, 2004;26:401-409.

Fireman, P. The mechanisms of allergic inflammation. The allergy and asthma report, WB Saunders Company. 1999.

Plaut,M.,Pierce,J.H.,et al. Mast cell lines produce lymphokines in response to cross-linkage of Fc epsilon

RI or to calcium ionophores. Nature.1989;339:64-67.

Wodnar-filipowicz, A., Heusser, C. H., Moroni, C. Production of the haemopoietic growth factors GM-CSF and interleukin-3 by mast cells in response to IgE receptor-mediated activation. Nature (London), 1989; 339:150-152.

Bradding, P., Wilson, S., et al. Immunolocal ization of interleukin-4 by mast cell. Journal of Immunology. 1993;151:3853-3865.

Semenza. Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology. Trends in Molecular Medicine,2001;7:345-350.

Wilmana,P.F.Analgesik-antiperitik, analgesik anti-inflamasi nonsteroid dan obat pirai. Dalam :Farmakologi dan terapi edisi 4. Jakarta: Balai Penerbit FKUI, 1995

Bellanti,J. A.Immunology II. Philadeiphia: WB Saunders Company, 1978; pp 471-490.

Abraham, S. N. & R. Malaviya. Mast cell in infection and immunity. Infect Immun. 1997;65:3501-3508

Kubes, P., Kanwar, S., Niu, X. F & Gaboury J. P. Nitric oxide synthesis inhibition induces leukocyte adhesion

via superoxide and mast cell. FASEB J. 1993;7:1293-1299.

Ganong WF. Buku ajar fisiologi kedokteran. Edisi 17. Editor dr. M. Djauhari Widjajakusumah. Penerbit buku

kedokteran EGC, 1999.

Kitamura. Heterogenity of mast cell and phenotypic change between subpopulations. Annu. Rev. Immunol. 1989;7:59-76.

Lantz, C. S., Boesiger, J. Song,C.H.,Mach, N,Kobayashi, T & Mulligan, R.C. Role of interleukin 3 in mast cell and Basophil development and parasite immunity. Nature. 1998; 392:90-93.

Jippo,T.,Morii,E.,Ito,A.,Kitamura,Y., Effect of Anatomical Distribution of Mast Cells on Their Defense

Function against Bacterial Infections : Demonstration Using Partially Mast Cell–deficient tg/tg Mice, The Journal of Experimental Medicine, 2003,(197), 11:p 1417-1425

Gilfillan, A.M., Tkaczyk, Ch. Integrated signaling pathways for mast cell activation. Nat. Rev. Immunol, 2006;6:218-230.

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Published

2013-03-11

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Research Article