Permasalahan Pemberian Obat pada Pasien Geriatri di Ruang Perawatan RSUD Saiful Anwar Malang
DOI:
https://doi.org/10.21776/ub.jkb.2014.028.02.15Abstract
Permasalahan terkait pemberian obat sering terjadi pada pasien yang menjalani perawatan di rumah sakit, dengan faktor risiko yang tersering  adalah polifarmasi dan peningkatan usia. Penelitian ditujukan untuk mengetahui deskripsi usia, jenis kelamin, jumlah obat dan  prevalensi adanya Permasalahan terkait pemberian obat (Drug Related Problem=DRP) pada pasien geriatri yang menjalani perawatan di Rumah Sakit. Penelitian kohort retrospektif  dengan pengambilan data sekunder pada  pasien geriatri (≥60 thn) di Ruang Perawatan RSUD Saiful Anwar Malang selama Periode Januari- Desember 2011. Penelitian ini  menunjukkan dari 150 subjek  55,3% adalah pria, rentang usia 60-65 tahun (28%),  66-70 tahun (36%), 71- 75 tahun (19,3%), >75 tahun (16,7%). Polifarmasi terjadi pada  72% pasien geriatri dengan prevalensi kejadian  DRP sebesar 72%. Penggunaan obat tersering yaitu antibiotik (73,3%), H2 antagonis (60,7%),  antihipertensi (46 %),  antiemetik (37,3%), NSAID ( 32%). Kejadian DRP tersering yaitu potensi interaksi obat (66%), dosis yang tidak tepat (17,3%) , pemakaian obat yang tidak perlu (16%), efek samping obat (14%), pemilihan jenis obat yang tidak tepat (8,7%). Potensi interaksi obat terbanyak yaitu pada obat ACE-inhibitor, diuretik dan antiplatelet. Duplikasi obat terjadi pada pemberian PPI dan H2 antagonis.  Terdapat hubungan yang signifikan antara peningkatan jumlah obat yang diberikan dengan prevalensi terjadinya DRP (p=0,000). Tidak terdapat hubungan yang signifikan antara peningkatan usia subjek dengan prevalensi DRP (p=0,366). Risiko relatif pasien geriatri dengan polifarmasi mengalami DRP  sebesar  1,822 (CI 95%: 1,291-2,569).
Kata Kunci: Geriatri, permasalahan terkait pemberian obat, polifarmasi
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