RESISTENSI OBAT MALARIA: MEKANISME DAN PERAN OBAT KOMBINASI OBAT ANTIMALARIA UNTUK MENCEGAH

Authors

  • Dorta Simamora Biologi Fakultas MIPA Universitas Satya Wyata Mandala (USWIM) Nabire-Papua
  • Loeki Enggar Fitri Laboratorium Parasitologi Fakultas Kedokteran Universitas Brawijaya Malang

DOI:

https://doi.org/10.21776/ub.jkb.2007.023.02.4

Abstract

Multi drug resistance (MDR) of malariae parasite iscaused by decreasing ability of some antimalarial  drugs examples chloroquine, mefloquine, antifolate and atovaquone  to Plasmodium. Resistance to artemisin has not beenfound yet. Antimalaria drug resistance happened because some factors especially : genetic factor (gene mutation)  of the Plasmodium. Mechanism pathway of resistance differsin location, because the different target drug action. Resistance migh be reduce by using combination therapy. Key words: resistance, Plasmodium falciparum, antimalaria combination

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References

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Published

2013-04-17

Issue

Vol. 23 No. 2 (2007)

Section

Research Article

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