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A 44 years Old Man with Chronic Myeloid Leucemia and mass at Right Lower Leg

ahadini islamiah, Shinta Oktya Wardhani
  Jurnal Kedokteran Brawijaya, Vol 29, No. 4 (2017),    

Abstract


Chronic myeloid leukemia, is a clonal myeloproliferative disorder of the primitive hematopoietic stem cell that is characterized by overproduction of cells of the myeloid series, splenomegaly and leukocytosis. A male, 44 years old, diagnosed as CML 3 years and took hydroxyurea but stopped due to economical problem, came to hospital with leg swollen and pain 3 months.  Clinical examination, laboratorium, radiology, and biopsy revealed results matched to CML and soft tissue mass,  FNAB of right leg mass showed histiocyte fragmented, multinucleated giant cells and cells with atypical nucleated, might be fibroma with atypical nucleated cells.  MRI showed soft tissue mass multilocular lobulated on poplitea region to cruris dextra, cyst mass high protein dd/ solid tumor with vascular encasement, lesion as bone marrow replacement, and fluid collection on parapatella burse.  Patient treated with hydroxyurea and showed improvement in clinical condition and also in decreasing of mass size.

Key words: Chronic myeloid leukemia, CML, mass leg, hydroxyurea


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References


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