Validation of TWIST (Testicular Workup for Ischemia and Suspected Torsion) Score System for Differential Diagnosis in Acute Scrotum in Tertiary Teaching Hospital
DOI:
https://doi.org/10.21776/ub.jkb.2022.032.01.4Keywords:
acute scrotum, diagnostic, testicular torsionAbstract
The acute scrotum is a common urological emergency and has a broad differential diagnosis. There is no clear consensus on a particular algorithm to follow in the diagnosis of testicular torsion. Testicular Workup for Ischemia and Suspected Torsion (TWIST) Score, a risk scoring system based on signs and symptoms, can be invaluable in managing patients with the acute scrotum, specifically testicular torsion. This study aimed to evaluate the effectiveness of the TWIST scoring system for differential diagnosis of acute scrotal patients. The study was conducted using secondary data, medical records from 111 male patients diagnosed with acute scrotum in Saiful Anwar General Hospital Malang between January 2015 and December 2018. Data about the onset of pain, first contact, history, physical examination findings, any adjunct test performed, and intra-operative findings were collected. The effectiveness of the TWIST score in diagnosing testicular torsion was determined by calculating the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). Of the 111 patients, 43 patients (38.7%) had testicular torsion. The mean age was 17.49 (6.69) years. A total of 39 patients were classified as high risk as per the TWIST Score with cut point 5 had 83.7% sensitivity, 95.6% specificity, 92.3% positive predictive value (PPV), and 90.3% negative predictive value (NPV). The area under the curve was 0.93. The use of the TWIST Score in clinical practice can accurately determine high-risk patients who can proceed straight to the operating theatre without the need for an ultrasound.
Downloads
References
Jefferies MT, Cox AC, Gupta A, and Proctor A. The Management of Acute Testicular Pain in Children and Adolescents. British Medical Journal (Clinical Research). 2015; 350: h1563.
Lee SM, Huh JK, Baek M, et al. Nationwide Epidemiological Study of Testicular Torsion in Korea. Journal of Korean Medical Science. 2014; 29(12): 1684-1687.
Srinivasan AK, Cinman N, Feber KM, Gitlin J, Palmer LS. History and Physical Examination Findings Predictive of Testicular Torsion: An Attempt to Promote Clinical Diagnosis by House Staff. Journal of Pediatric Urology. 2011; 7(4): 470–474.
Ta A, D'Arcy FT, Hoag N, and Lawrentschuk N. Testicular Torsion and the Acute Scrotum: Current Emergency Management. European Journal of Emergency Medicine. 2016; 23(3): 160-165.
Moosaje SH. A Validation of the “TWIST” Score in Diagnosis of Acute Testicular Torsion in the Acute Scrotum in Kenyatta National Hospital. [Thesis]. University of Nairobi, Nairobi. 2017.
Barbosa JA, Tiseo BC, Barayan GA, et al. Development and Initial Validation of a Scoring System to Diagnose Testicular Torsion in Children. The Journal of Urology. 2013; 189(5): 1859-1864.
Zhao LC, Lautz TB, Meeks JJ, and Maizels M. Pediatric Testicular Torsion Epidemiology Using a National Database: Incidence, Risk of Orchiectomy and Possible Measures Toward Improving the Quality of Care. The Journal of Urology. 2011; 186(5): 2009-2013
Tekgül S, Dogan HS, Kocvara R, et al. EAU Guidelines on Paediatric Urology. (Online) 2017. https://uroweb.org/wp-content/uploads/Paediatric-Urology-2017-pocket.pdf
Frohlich LC, Paydar-Darian N, Cilento BG, and Lee LK. Prospective Validation of Clinical Score for Males Presenting with an Acute Scrotum. Academic Emergency Medicine. 2017; 24(12): 1474–82.
Sheth KR, Keays M, Grimsby GM, et al. Diagnosing Testicular Torsion before Urological Consultation and Imaging: Validation of the TWIST Score. The Journal of Urology. June 2016; 195(6): 1870-1876.
Indradiputra IMU, Daryanto B, Seputra KP, Satyagraha P, and Nurhadi P. Clinical Risk Factors for Non Salvageable Testis in Pediatric and Adult Testicular Torsion Patients. European Urology Supplements. 2017; 16(3): e1192.
Boettcher M, Krebs T, Bergholz R, Wenke K, Aronson D, and Reinshagen K. Clinical and Sonographic Features Predict Testicular Torsion in Children: A Prospective Study. BJU International. 2013; 112(8): 1201-1206.
Gajbhiye AS, Shamkuwar A, Surana K, Jivghale K, and Soni MK. Surgical Management of Testicular Torsion. International Surgery Journal. 2016; 3(1): 195-200.
Fehér ÁM and Bajory Z. A Review of Main Controversial Aspects of Acute Testicular Torsion. Journal of Acute Disease. 2016; 5(1): 1-8.
Downloads
Published
Versions
- 2022-04-09 (5)
- 2022-04-09 (4)
- 2022-03-04 (3)
- 2022-02-28 (2)
- 2022-02-28 (1)
Issue
Section
License
Authors who publish with this journal agree to the following terms:- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).