Prevalensi Infeksi Hepatitis B pada Ibu Hamil di Malang

Authors

  • Syifa Mustika Universitas Brawijaya
  • Dian Hasanah Universitas Brawijaya

DOI:

https://doi.org/10.21776/ub.jkb.2018.030.01.13

Keywords:

Anti-HBs, HBsAg, hepatitis B, kehamilan

Abstract

Ibu hamil yang terinfeksi hepatitis B dapat menularkan virus ke bayi mereka selama kehamilan atau persalinan, sehingga penapisan perlu dilakukan untuk mengetahui prevalensi ibu hamil yang mengidap hepatitis B di wilayah Malang. Penapisan dilaksanakan di dua Puskesmas Kota Malang yaitu Dinoyo dan Kedungkandang, dua Puskesmas Kabupaten Malang yaitu Sumberpucung dan Gondanglegi, serta RS Hermina. Peserta diberikan penyuluhan, dilakukan anamnesis, pemeriksaan tanda-tanda vital, dan pengumpulan sampel darah pada ibu hamil yang setuju berpartisipasi. Serum peserta dilakukan pemeriksaan HBsAg dan Anti-HBS, metode yang digunakan adalah ELISA. Terdapat 156 ibu hamil mengikuti penapisan. Rerata usia peserta adalah 28,55,8 tahun dan rerata usia saat menikah adalah 22,53,8 tahun. Didapatkan prevalensi hepatitis B sebesar 1% dan 8% anti-HBs yang positif pada pasien dengan HBsAg negatif. Data ini diharapkan menjadi dasar kebijakan tentang pencegahan hepatitis B, seperti penggalakan vaksinasi hepatitis B dan edukasi hepatitis B ke populasi yang lebih luas.

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References

World Health Organization. Guidelines for the Prevention Care and Treatment of Persons with Chronic Hepatitis B Infection. Geneva: World Health Organization; 2015

Ugbebor O, Aigbirior M, Osazuwa F, Enabudoso E, and Zabayo O. The Prevalence of Hepatitis B and C Viral Infections among Pregnant Women. North American Journal of Medical Sciences. 2011; 3(5): 238-241.

Mishra S, Purandre P, Thakur R, Agrawal S, and Alwani M. Study on Prevalence of Hepatitis B in Pregnant Women and Its Effect on Maternal and Fetal Outcome at Tertiary Care Centre. International Journal of Reproduction, Contraception, Obstetrics, and Gynecology. 2017; 6(6): 2238-2240.

Fernandes CNS, Alves MM, de Souza ML, Machado GA, Couto G, and Evangelista RA. Prevalence of Hepatitis B and C Seropositivity in Pregnant Women. Revista da Escola de Enfermagem da USP. 2014; 48(1): 91-98.

Cui A, Cheng X, Shao J, et al. Maternal Hepatitis B Virus Carrier Status and Pregnancy Outcomes: A Prospective Cohort Study. BMC Pregnancy and Childbirth. 2016; 16(87): 1-8.

Rita, Thaker B, Bhat S, and Sharma S. Prevalence of Hepatitis-B Surface Antigen among Pregnant Women with Maternal and Perinatal Outcome. International Journal of Tropical Medicine and Public Health. 2012; 1(2): 8-17.

Kementerian Kesehatan Republik Indonesia. Profil Kesehatan Indonesia. Jakarta: Kementerian Kesehatan Republik Indonesia; 2014.

Bayo P, Ochola E, Oleo C, and Mwaka AD. High Prevalence of Hepatitis B Virus Infection among Pregnant Women Attending Antenatal Care: A Cross-Sectional Study in Two Hospitals in Northern Uganda. British Medical Journal Open. 2014; 4(11): 1-7.

Badan Penyelenggara Jaminan Kesehatan. Panduan Praktis Administrasi Klaim Faskes BPJS Kesehatan. Jakarta: Badan Penyelenggara Jaminan Kesehatan; 2014.

Kementerian Kesehatan Republik Indonesia. Pusat Data dan Informasi. Jakarta: Kementerian Kesehatan Republik Indonesia; 2014.

Dyson JK, Waller J, Turley A, et al. Hepatitis B in Pregnancy. Frontline Gastroenterology. 2014; 5(2): 111-117.

Suyoso, Mustika S, and Harijono A. Ensefalopati Hepatik pada Sirosis Hati: Faktor Presipitasi dan Luaran Perawatan di RSUD dr. Saiful Anwar Malang. Jurnal Kedokteran Brawijaya. 2015; 28(4): 340-344.

Tran TT. Hepatitis B Virus in Pregnancy. Clinical Liver Disease, 2013; 2(1): 29-33.

Souzaa MT, de Pinho TLR, Santos MDC, et al. Prevalence of Hepatitis B among Pregnant Women Assisted at the Public Maternity Hospitals of São Luís, Maranhão, Brazil. The Brazil Journal of Infectious Disease. 2012; 16(6): 517–520.

Kuru U, Turan O, Kuru N, et al. Prevalence of Hepatitis B Virus Infection in Pregnant Turkish Women and Their Families. European Journal of Clinical Microbiology and Infectious Disease. 1996; 15(3): 248-251.

Leung N. Chronic Hepatitis B in Asian Women of Childbearing Age. Hepatology International. 2009; 3(1): 24-31.

Wen WH, Chang MH, Zhao LL, et al. Mother-to-Infant Transmission of Hepatitis B Virus Infection: Significance of Maternal Viral Load and Strategies for Intervention. Journal of Hepatology, 2013; 59(1): 24-30.

Lao TT, Sahota DS, Law LW, Cheng YKY, and Leung TY. Age-Specific Prevalence of Hepatitis B Virus Infection in Young Pregnant Women, Hong Kong Special Administrative Region of China. Bulletin of the World Health Organization. 2014; 92(11): 782-789.

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Published

2018-02-28

Issue

Vol 30, No. 1 (2018)

Section

Case Report

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