TERAPI BIOLOGIK PADA PASIEN PSORIASIS
DOI:
https://doi.org/10.21776/ub.jkb.2008.024.03.6Abstract
ABSTRACTTreatment limitations of current immunosuppressive therapies, and growing understanding of psoriasis
pathogenesis on a molecular level have stimulated much interest in the field of immunomodulatory therapy fo
management of psoriasis. Genetic engineering has allowed the development of proteins that are targeted to
specific cell surface receptors. A well over 40 targeted biologic agents are in preclinical and clinical testing fo
T-cell mediated inflammatory   diseases, including psoriasis. It is important that, as a doctor become wel
educated in biologics, since several of these agents are available for the management of psoriasis. Â
Keywords: immunosuppressive therapy, immunomodulatory therapy, genetic engineering, surface receptors, targeted
biologic agents, biologics.
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