EFEK EKSTRAK BUAH TOMAT (Licopersicum pyriforme) TERHADAP EKSP KOLAGEN TIPE 1, MMP-1 DAN MMP-3 PADA PENUAAN KULIT
DOI:
https://doi.org/10.21776/ub.jkb.2008.024.03.1Abstract
ABSTRACTMany theory and research was trying to explain the aging process. Free radical theory explained that all
normal metabolism process in the body can produce free radical.These free radical can destroy the skin cell,
and than the skin will start the aging process. The tomato extract has antioxidant such as lycopene, β-
carotene and vitamin C. These antioxidant will prevent the activity of free radical, so that skin cell will not
damage. The aims of this research were to study effect of tomato extract juice in preventing skin aging on
wistar rats. Total of 25 rats were divided into 5 groups, consisted of 5 rats each. Group one was control group
D-0) rats were four months old, and the group two control of group rats were taken care of 4 months old until
7 months old (D-1), the other group which were under treatment classified into 3 groups. Group three were
ed 7 g/kg/day/ body weight of tomato fruit extract, then taken care of 4 months old until 7 months old (D-2),
group four were fed 11 g/kg/day/ body weight of tomato extract fruit, then taken care of 4 months old until 7
months old (D-3) and group five were fed 15 g/kg/day/ body weigh of tomato fruit extract, then taken care of 4
months old until 7 months old (D-4).
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