PENGARUH PEMBERIAN KAPSUL EKSTRAK GARLIK TERHADAP PERUBAHAN TEKANAN DARAH DAN JUMLAH TROMBOSIT PADA PENDERITA PREEKLAMPSI RINGAN

Authors

  • Yahya Irwanto Sub Bagian Fetomaternal SMF Obstetri dan GinekologiFK Unibraw/ RSU Dr. Saiful Anwar Malang
  • Imam Wahyudi Sub Bagian Fetomaternal SMF Obstetri dan GinekologiFK Unibraw/ RSU Dr. Saiful Anwar Malang
  • Soetomo Soewarto Sub Bagian Fetomaternal SMF Obstetri dan GinekologiFK Unibraw/ RSU Dr. Saiful Anwar Malang

DOI:

https://doi.org/10.21776/ub.jkb.2004.020.03.8

Abstract

The objectives is to investigate the efectivity of  extract garlic capsule compared to standart therapytoward the changes of blood presure and thrombocyt level in the mild-preeclampsy patients. This study was a single-blind randomised clinical trial. The subject of study were the mild-preeclampsy pregnant women within 20 – 36 weeks of gestational age whose came to the Poli Hamil RSUD dr. Saiful Anwar. The subject divided into 2 groups, the treatment group received both of the standart therapy of mild-preeclampsy and extract garlic capsule, while the controlling grouponly received the standart therapy of mild-preeclampsy. After 2 weeks, the blood pressure and the trombocyt count was evaluated. Thesystolic blood pressure of the treatment group wasdecrease at average of 10.12 mmHg, from 140.25 ± 5.57 before treatment to 130.12 ± 10.84 mmHg after treatment, while in thecontrololling group there was an increase at average of 5.56 mmHg from 140.44± 6.14 mmHg to 146±13.81 mmHg. The T Test and ANCOVA analyzing showed a significant result (P value were 0.001 and0.0008).

Downloads

Download data is not yet available.

References

DAFTAR KEPUSTAKAAN

Dekker GA, Sibai BM. Etiology and Pathogenesis of Preeclamsia: Cureent concept. Am J Obstet Gynecol 1998; 179: 1275-1278.

Mose JC. Prevention of Preeclamsia. Surabaya: The Scientific Meeting On Fetomaternal Medicine; 2002.

Angsar MD. EPH Gestosis Dalam Prespektiv. Surabaya: UPF Obstetri & Ginekologi Fak. Kedokteran Universitas Airlangga RSUD Dr. Sutomo.

Angsar D, Simanjuntak P, Handaya, Sjahid S. Satgas Gestosis POGI KOGI VI Ujung Pandang; 1985.

Jesse J, Mohseni M, Shah. Medical Attributes of Allium Sativum-garlic. http://wilkes.edu/kklemow/allium.html

Meizia D. Comparison of Nitric Oxide Serum Level And PlateletCount In Mild Preeklamsia Before And After Garlic (Allium Sativum) Treatment And Its Corellation With Blood Pressure. Fakultas Kedokteran Universitas Padjajaran Bandung:Thesis; 2000.

Soranna D, Hirani J, Das I. Garlic and Pregnancy. http://www.mistral.co.uk/garlic/preg.htm

Soranna D, Hirani J, Khan N, Das I. Garlic and Nitric Oxide Metabolism: The Implication During Pregnancy In

http://www.mistral.co.uk/garlic/g_and_no.htm

Siegal G, Casper U, Walter A. Changes in Vascular Tone And Calcium Metabolism. http://www.garweb@mistral.co.uk

Neil A, Silagy C. A Meta Analysis of The Effect of Garlic on Blood Pressure and Serum Lipids. http://www3.mistral.co.uk/garlic/metaanal.htm

Kemper KJ. Clinician Information Summary: Garlic, in http://www.mcp.edu/herbal/default.htm.

Therapeutic use of garlic in http://www.carolnored.mybravenet.com/Monograph/GARLIC/garlic.HTM

Rahman K, Billington D. Dietery Supplementation with Aged Garlic Extract Inhibits Adp-Induced Platelet Agregation In Human. Jounal of Nutrition; 2000; 130: 2662-2665.

Lawson LD, Ransom DK, Hughes BG. Inhibition of Whole Blood Platelet-Agregation Bay Compounds In Garlic Clove Extract And Comercial Garlic Powder Product. Thromb Res;1992;65:141-156.

Ryu K, Ide N, Matsura H, Itakura Y. Nα-(1-Deoxy-d-fruktosa)-L-Arginine, an Antioksidan Compound Identified In Aged Garlic Exstract. Jornal of Nutrition 2001; 131: 972S-976S.

Downloads

Published

2013-04-16

Issue

Section

Research Article