Hubungan Polimorfisme Gen ACTN3 dengan Kelincahan, Daya Ledak, dan Kecepatan

Authors

  • susiana candrawati Universitas Jenderal Soedirman
  • Nur Signa Aini Gumilas Universitas Jenderal Soedirman
  • Muhammad Nanang Himawan Kusuma Universitas Jenderal Soedirman
  • Pradani Eva Adiningtyas Universitas Jenderal Soedirman
  • Muhammad Cahya Riadi Sucipto Universitas Jenderal Soedirman
  • Sarah Shafira Aulia Rahmah Universitas Jenderal Soedirman

DOI:

https://doi.org/10.21776/ub.jkb.2017.029.04.8

Keywords:

Daya ledak, kecepatan, kelincahan, polimorfisme gen ACTN3, sepak bola

Abstract

Komponen biomotorik kelincahan, daya ledak, dan kecepatan merupakan komponen yang harus dimiliki atlet sepak bola. Penelusuran genetik dapat menjadi salah satu metode talent profiling pada atlet sepak bola. Talent profiling belum pernah dilakukan pada kalangan atlet Indonesia terutama atlet yunior seperti atlet Unit Kegiatan Mahasiswa (UKM) Sepak Bola di (Universitas Jenderal Soedirman) UNSOED. Salah satu gen yang berhubungan dengan performa adalah gen ACTN3. Gen ACTN3 yang merupakan gen pengkode protein α-aktinin-3 pada serabut otot tipe cepat, diduga berpengaruh terhadap kelincahan, daya ledak dan kecepatan. Tujuan penelitian ini adalah untuk mengetahui hubungan polimorfisme gen ACTN3 dengan kelincahan, daya ledak dan kecepatan otot pada atlet sepakbola. Penelitian ini menggunakan rancangan studi observasional analitik dengan pendekatan cross sectional. Metode pengumpulan subjek pada penelitian ini menggunakan consecutive sampling. Subjek pada penelitian ini adalah 82 atlet yang mengikuti UKM sepak bola Universitas Jenderal Soedirman. Metode PCR-RFLP dan elektroforesis digunakan untuk melihat polimorfisme gen ACTN3. Sedangkan pengukuran komponen biomotorik menggunakan tes agilitas Illinois (kelincahan), jump meter digital (daya ledak) dan tes sprint 30 meter (kecepatan). Analisis data menggunakan uji ANOVA satu arah dengan tingkat kemaknaan p=0,05. Terdapat hubungan bermakna antara polimorfisme gen ACTN3 dengan daya ledak otot (p=0,027) dan tidak terdapat hubungan bermakna antara polimorfisme gen ACTN 3 dengan kelincahan (p=0,084) dan kecepatan (p=0,507). Rerata terbaik ketiga komponen biomotorik terdapat pada alel RR gen ACTN 3. Disimpulkan terdapat hubungan antara polimorfisme gen ACTN3 dengan daya ledak otot, tapi tidak terdapat hubungan antara polimorfisme gen ACTN 3 dengan kelincahan dan kecepatan pada atlet sepakbola.

Downloads

Download data is not yet available.

Author Biographies

susiana candrawati, Universitas Jenderal Soedirman

Fisiologi Kedokteran

 

Nur Signa Aini Gumilas, Universitas Jenderal Soedirman

Histologi Kedokteran

Muhammad Nanang Himawan Kusuma, Universitas Jenderal Soedirman

PJKR Fakultas Ilmu Kesehatan

Pradani Eva Adiningtyas, Universitas Jenderal Soedirman

Fakultas Kedokteran

Muhammad Cahya Riadi Sucipto, Universitas Jenderal Soedirman

Fakultas Kedokteran

Sarah Shafira Aulia Rahmah, Universitas Jenderal Soedirman

Fakultas Kedokteran

References

Anonim. Daftar Peringkat Dunia versi FIFA (Federation Internationale de Football Association) Edisi Februari 2013. (Online) 15 Februari 2013. http://www.fifa.com/fifa-world-ranking/associations/association=idn/men/index.html. [diakses tanggal 20 April 2013]

Bompa TO and Michael C. Periodization: Theory and Methodology of Training. Fifth Edition. Champaign: Human Kinetics; 2009.

Kusuma MNH, Dreisiglier T, and Portela J. Affecting Factors of Plyometric Exercise on Jumping Performance. Journal of Sports Medicine and Applied Physiology Germany. 2012; 52: 121.

Parahita A. Pengaruh Latihan Fisik Terprogram Terhadap Daya Tahan Otot pada Siswi Sekolah Bola Voli Tugu Muda Semarang Usia 9-12 Tahun. [Thesis]. Fakultas Kedokteran Universitas Diponegoro, Semarang. 2009.

American Dietetic Association, Dietitians of Canada, American College of Sports Medicine, Rodriguez NR, Di Marco NM, and Langley S. American College of Sports Medicine Position Stand. Nutrition and Athletic Performance. Medicine and Science in Sports and Exercise. 2009; 41(3): 709-731.

Mayne I. Examination of the ACE and ACTN-3 Genes in UTC Varsity Athletes and Sedentary Students. [Thesis]. The University of Tennessee, Chattanooga. 2006.

Ma F, Yang Y, Li X, et al. The Association of Sport Performance with ACE and ACTN3 Genetic Polymorphisms: A Systematic Review and Meta-Analysis. Sport Performance and Human Genetic Polymorphisms. 2013; 8(1): 1-9.

Mac Arthur DG and North KN. ACTN3: A Genetic Influence on Muscle Function and Athletic Performance. Exercise and Sports Sciences Reviews. 2007; 35(1): 30-34.

Cieszczyk P, Sawczuk M, Karlowska AM, and Ficek K. ACTN3 R577X Polymorphism in Top-Level Polish Rowers. Journal of Exercise Science and Fitness. 2012; 10: 12-15.

Massida M, Corrias L, Scorcu M, Vona G, and Calo MC. ACTN3 and ACE Genotypes in Elite Male Italian Athletes. Anthropological Review. 2012; 75(1): 51-59.

Moran CN, Yang N, Bailey ME, et al. Association Analysis of the ACTN3 R577X Polymorphism and Complex Quantitative Body Composition and Performance Phenotypes in Adolescent Greeks. European Journal of Human Genetics. 2007; 15(1): 88–93.

North K. Why is α-Actinin-3 Deficiency So Common in the General Population? The Evolution of Athletic Performance. Twin Research and Human Genetics. 2008; 11(4): 384-394.

Paparini A, Ripani M, Giordan, GD, Santoni D, Piqozzi F, and Romano SV. ACTN3 Genotyping by Real-Time PCR in the Italian Population and Athletes. Medicine Science Sports Exercise. 2007; 39(5): 810-815.

Lanxiang He and Jie W. ACTN3 Polymorphism for Athletes of Han Nationality in Southwestern China. Journal of Chengdu Sport University. 2010; 2; 80-83, 88.

Goel H and Mittal B. ACTN3: Athlete Gene Prevalence in North India. Current Science. 2007; 92(1): 84-86.

Pimenta EM, Coelho DB, Veneroso CE, et al. Effect of ACTN3 Gene on Strength and Endurance in Soccer Players. The Journal of Strength and Conditioning Research. 2013; 27(12): 3286-3292.

Federation of International Lacrosse. Referee Fitness Testing Protocol. (Online) 2012. http://filacrosse.com/wpcontent/themes/sportedge/downloads/FIL_Referee_Fitness_Testing_Protocol.pdf. [diakses tanggal 18 Juli 2013].

Goedecke JH, White NJ, Chicktay W, Mahomed H, Durandt J, and Lambert MI. The Effect of Carbohydrate Ingestion on Performance during a Simulated Soccer Match. Nutrients. 2013; 5(12): 5193-5204.

Delecluse C, Roelants M, Diels R, Koninckx E, and Verschueren S. Effect of Whole Body Vibration Training on Muscle Strength and Sprint Performance in Sprint Trained Athlete. International Journal of Sports Medicine. 2005; 26(8): 662-668.

Clarkson PM, Devaney JM, Dressman HG, et al. ACTN3 Genotype is Associated with Increases in Muscle Strength in Response to Resistance Training in Women. Journal of Applied Physiology. 2005; 99: 154-163.

Delmonico MJ, Kostek MC, Doldo NA, et al. Alpha-Actinin-3 (ACTN3) R577X Polymorphism Influences Knee Extensor Peak Power Response to Strength Training in Older Men and Women. Journals of Gerontology. 2007; 62(2): 206-212.

Jung H, Lee N, and Park S. Interaction of ACTN3 Gene Polymorphism and Muscle Imbalance Effects on Kinematic Efficiency in Combat Sports Athletes. Journal Exercise Nutrition & Biochemistry. 2016; 20(2): 1-7.

Alfred T, Ben-Shlomo Y, Cooper R, et al. ACTN3 Genotype, Athletic Status, and Life Course Physical Capability: Meta-analysis of the Published Literature and Findings from Nine Studies. Human Mutation. 2011; 32(9): 1008-1018.

Norman B, Esbjornsson M, Rundqvist H, Osterlund T, Von Walden F, and Tesch PA. Strength, Power, Fiber Types, and mRNA Expression in Trained Men and Women with Different ACTN3 R577X Genotypes. Journal Applied Physiology. 2009; 106(3): 959–965.

AG Nur Signa, Candrawati S, dan HK Mohammad Nanang. Hubungan Polimorfisme Gen ACTN3 dengan Performa Otot pada Atlet UKM Sepak Bola Universitas Jenderal Soedirman. Jurnal Kedokteran Brawijaya. 2016; 29(1): 74-78.

Eynon N, Ruis JJ, Femia P, et al. The ACTN3 R577X Polymorphism across Three Groups Elite Male European Athletes. PLOS ONE. 2012; 7(8): 1-7.

Ahmetov II, Donnikov AE, and Trofimov DY. ACTN3 Genotype is Assosiated with Testoterone Levels of Athletes. Biology of Sport. 2014; 31(2): 105-108.

Urban RJ. Growth Hormone and Testosterone: Anabolic Effects on Muscle. Hormone Research in Paediatrics Journal. 2011; 76(1): 81-83.

Downloads

Published

2017-08-31

Issue

Section

Research Article