Penggunaan Suksinilkolin Setelah Tidak Meningkatkan Kadar Kalium Plasma Pasien dengan Cedera Kepala Berat

Authors

  • Wahyuni Dian Purwati Emergency Medicine, Fakultas Kedokteran Universitas Brawijaya/RSU Dr. Saiful Anwar Malang
  • Viera Wardhani Laboratorium Ilmu Kesehatan Masyarakat, Fakultas Kedokteran Universitas Brawijaya
  • Gunung Mahameru Laboratorium Anestesiologi dan Reanimasi, Fakultas Kedokteran Universitas Brawijaya
  • Mohamad Istiadjid Laboratorium Bedah Saraf, Fakultas Kedokteran Universitas Brawijaya/RSU Dr. Saiful Anwar Malang

DOI:

https://doi.org/10.21776/ub.jkb.2009.025.02.4

Abstract

This study aimed to identify the changes of plasma potassium level after intubation with rapid sequenceintubation method in severe head injury patients using succinylcholine as muscle relaxant. Subjects aresevere head injury patients with glasgow coma scale (GCS) ≤ 8. Plasma potassium level was measured twice,before intubation and (minutes 5, 10, 15, 20) after intubation. Another variable that also measured were bloodgas analyze, time intubated and injury in another organ. There were 34 patients who came to EmergencyDepartment (ED) of Saiful Anwar General Hospital since January until April 2009. Mean level of plasmapotassium changes after intubation minute 5 (-0.01529); minute 10 (-0.01971); minute 15 (0.04147); minute20 (0.00059). Statistical analysis using paired t test revealed no significance of this difference (p>0.05). Therewere no changes of plasma potassium level in severe head injury patients after intubation withsuccinylcholine

Downloads

Download data is not yet available.

References

Kirsch TD, Lipinski CA, Head Injury. Di dalam: Tintinalli JE, Kelen GD, Stapczynski JS (ed). Emergency Medicine, A Comprehensive Study guide. 6 th ed. Singapore: McGraw-Hill; 2004: 1557-1569.

Heegaard WG, Biros MH. Head. Di dalam: Marx JA, Hockberger RS, Walls RM, Adams JC, Barsan WG, Biros MH et al (ed). Rosen's Emergency Medicine Concepts and Clinical Practice. 6th ed. Vol 1. Philadelphia: Mosby Inc; 2006: 349-382.

SMF Bedah Saraf RS Dr. Saiful Anwar. Rekapitulasi data pasien cedera Kepala Berat tahun 2007. Malang: Bagian Bedah Saraf RS Dr. Saiful Anwar; 2007.

Reichman E, Simon RR. Emergency medicine procedure. California: McGraw-Hill; 2004.

Stevenson PH, Birch A. Succinylcholine- induced hyperkalemia in a patient with closed head injury. Anesthesiology 1979; 51: 89-90

Frankville DD, Drummond JC. Hyperkalemia after succinylcholine administration in patient with closed head injury without paresis. Anesthesiology 1987; 67: 264-266.

Dahlan MS. Statistik untuk kedokteran dan kesehatan. Edisi 3. Jakarta: Salemba Medika; 2008.

Sastroasmoro S, Ismael S. Dasar-dasar metodologi penelitian klinis. Jakarta: Binarupa Aksara; 1995.

Bullock R, Chestnut RM, Clifton G, . et al. Guidelines for the management of severe head injury. New York, NY: Brain Trauma Foundation; 2000.

Evers W, Racz Gabor B, Dobkin AB. A Study Of plasma potassium and electrocardiographic changes after single dose of succinylcholine. Can Anaes Soc J 1969;16: 273-278.

Munford B. Practical pharmacology of neuromuscular blockade. Air Medical Journal 1998; 17(4):149-156 .

Orebaugh SL. Succinylcholine: adverse effects and alternatives in emergency medicine. Am J Emerg Med 1999; 17(7): 715.

Schneider RE, Caro DA. Neuromuscular Blocking Agent. Di dalam: Walls RM (ed). Manual of emergency airway management . 2 nd ed. Lipincot Williams & Wilkins; 2004:209-260.

Morgan GE, Mikhail MS, Murray MJ. Clinical anesthesiology. 4 th ed. California: McGraw-Hill; 2006.

Schow AJ, Lubarsky DA, Olson RP, Gan TJ. Can succinylcholine be used safely in hyperkalemic patients? Anesth Analg 2002; 95: 119-22.

Kovarik WD, Mayberg TS, Lam AM, Mathisen TL, Winn HR. Succinylcholine does not change intracranial pressure, cerebral blood flow velocity, or the electroencephalogram in patients with neurologic injury . Anesth Analg 1994; 78: 469-73.

Downloads

Published

2013-03-14

Issue

Vol. 25 No. 2 (2009)

Section

Research Article

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

Most read articles by the same author(s)